Touhey attended Princeton University, and was a member of the Peace Corps. He was the managing partner of the Latham Four Partnership, which manages apartments
offices, and distribution facilities in Arizona, Florida, New York and Texas. He was president of The Spare Room Inc., an Albany storage facility with over 3,000 unites. Touehy was also previously Vice President of Orange Motor Company, Albany. His career was focused on building affordable housing in Arbor Hill. Touhey was on the Albany Board of Education from 1976-1981.
He was chairman of the Board of Trustees of WMHT Public Television 1991-95. Touhey is interested in incorporating cultural inclusion into school curriculum Touhey founded the Touhey Family Foundation, or the Charles L. Touhey Foundation, that awards grants to teachers and schools that pursue culturally relevant teaching projects. In 2007, the foundation supplied more than 150 Albany public school teachers with culturally responsive teaching materials. Through a grant from Donors Choose, the foundation funded culturally responsive teaching proposals designed by Albany public school teachers. The Touhey Family Foundation was one of the first donors and supporters for the Pediatric Emergency Dept at Albany Medical Center.  Touhey is a Professor of the Africana Studies Department at the University of Albany.
Touhey was chosen in 2002 by Albany Mayor Gerald D. Jennings to work on the Arbor Hill Revitalization Task Force, and oversaw the building of 50 owner-occupied, two-family homes. He has served on a number of boards, including the Board for the Center for Law and Justice, and is a trustee for the College of St. Rose. He is a board member of the Albany Center for Economic Success, a small business incubator that assists women and minority entrepreneurs in starting up new enterprises Charles Touhey received the Joseph A. Bosco Community Service Award in 2011. Touhey has been involved in Capital Region for many years. He was the managing partner of The Latham Four Partnership in 2011, and oversaw a million square feet of offices and distribution facilities in New York and Florida. He has developed several residential subdivisions using such innovations as modular housing. On June 16, 2018 he was appointed as an honorary member of Operation Crossroads Africa, a non-profit organization that brings volunteers to Africa to Africa in order to engage in chores and projects with native African people for 6 weeks in the summer.